Comparison of Electroacupuncture to Mirabegron for Treatment of Overactive Bladder

• Status: Withdrawn
• Trial end date: 2018-09-30
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares electroacupuncture to mirabegron for treatment of overactive bladder (OAB) symptoms in women who have failed treatment with anticholingeric therapy.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospitals Cleveland Medical Center
• Treatments: Mirabegron

Criteria

Inclusion Criteria:

• - Patients must be 18 years or older as well as willing and able to provide informed consent

• Patients with documented symptoms of overactive bladder including: urgency, frequency >7 times per day, nocturia, urgency incontinence for at least 6 months

• Patients who have failed at least one anti-cholinergic medication defined as no change or unsatisfactory improvement in symptom severity after 6 weeks of a daily regimen

Exclusion Criteria:

• Patients younger than 18 years,

• Patients unable or unwilling to provide informed consent,

• Patients who are illiterate,

• Patients who are non-English speaking or reading,

• Patients with a current urinary tract infection

• Patients with a history of interstitial cystitis

• Patients who have a history of a bleeding disorder

• Patients who are currently on chronic anti-coagulation

• Patients who are have taken mirabegron in the past or are currently using it

• Patients currently undergoing acupuncture treatment for a different condition

• Patients who are currently undergoing pelvic floor physical therapy

• Patients who are currently undergoing or will undergo treatment for a urologic or gynecologic malignancy

• Patients who are currently pregnant

• Patients with an implanted pacemaker or AICD

• Patients with a history of uncontrolled or poorly controlled hypertension