Comparison of Emergence and Oxygenation During One-lung Ventilation With Desflurane and Propofol Anesthesia

• Status: Active, not recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Which is more adequate general anesthetic agent, desflurane or propofol, for emergence and recovery time, and perioperative oxygenation in lung resection surgery?

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Juntendo University
• Collaborator: Baxter Healthcare Corporation
• Treatments: Anesthetics; Desflurane; Isoflurane; Propofol

Criteria

Inclusion Criteria:

• Patients agree to participate in the study

• Patients undergoing lung cancer surgery requiring one-lung ventilation.

• American Society of Anesthesiologists Physical Status Class 1 or 2

Exclusion Criteria:

• Patients with any of the following will be excluded from lung cancer patients.

• New York Heart Association Classification more than 2

• Respiratory dysfunction Vital Capacity or percent predicted Forced expiratory volume in one second is less than 50 %

• Pulmonary hypertension with mean pulmonary arterial pressure more than 30 mmHg

• Coagulation dysfunction

• The administration of steroids and immunosuppressive agents within 3 months prior to surgery

• Infection with active inflammation

• Pneumonectomy patients

• Cases of epidural anesthesia is contraindicated