Overview

Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum

Status:
Completed
Trial end date:
2019-11-01
Target enrollment:
Participant gender:
Summary
The investigators will compare the effectiveness of gabapentin to metoclopramide for 1 week among 60 women with hyperemesis gravidarum (HG) in this randomized, double-blinded trial. After completion of the 1-week double-blind phase, subjects will be offered open-label gabapentin with rescue metoclopramide until their symptoms no longer require treatment. Enrollment will occur at the University's at Buffalo, of Rochester and of Wisconsin.
Phase:
Phase 2
Details
Lead Sponsor:
University at Buffalo
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Treatments:
Gabapentin
gamma-Aminobutyric Acid
Metoclopramide