Comparison of Hypoglycaemic Regimens During Ramadan Fasting in Type 2 Diabetes

• Status: Completed
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

Type 2 diabetic patients who fast during Ramadan experience swings in glycaemic control between hypoglycaemic troughs and hyperglycaemic spikes. Hence, the dual challenge in fasting diabetics is to identify which treatment modality leads to the most stable blood glucose levels during a fast and how to smooth out these excursions and reduce risks of fast to a minimum.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Services Hospital, Lahore
• Treatments: Acarbose; Hypoglycemic Agents; Metformin; Sitagliptin Phosphate

Criteria

Inclusion Criteria:

• HbA1c 6.5-9.5%.

• Type 2 diabetics on two or less oral hypoglycaemic agents.

Exclusion Criteria:

• Any contraindications either to fasting or to any of the trial medication.

• Pregnancy.

• Serum creatinine > 1.4 mg/dl.

• Serum ALT > twice upper limit normal.

• History of pancreatitis, serum amylase > twice upper limit normal.

• History of intolerance to acarbose.