Comparison of Insulin Glargine and NPH Insulin at Night and at Hypoglycemia in Type 2 Diabetes
Status:
Completed
Trial end date:
2006-03-01
Target enrollment:
Participant gender:
Summary
Long-acting insulin injected at bedtime may cause hypoglycemia (low blood sugar) in the night
in patients with diabetes. The aims of the study are 1) to compare the dynamic
characteristics of long-acting insulin analog glargine with those of NPH insulin and placebo
during the night and the early morning hours, 2) investigate differences on glucose
metabolism of bedtime glargine versus NPH insulin at induced hypoglycemia.