Comparison of Intravenous Co-amoxiclav Versus Benzyl Penicillin

• Status: Completed
• Trial end date: 2019-11-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare intravenous Co-amoxiclav versus Benzyl penicillin in children with severe streptococcal tonsillitis in terms of efficacy, safety and cost effectiveness.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Combined Military Hospital, Pakistan
• Treatments: Amoxicillin-Potassium Clavulanate Combination; Penicillin G; Penicillin G Benzathine; Penicillin G Procaine; Penicillins

Criteria

Inclusion Criteria:

1. Children who had 3 or 4 score according to Centor Criteria for tonsillitis/pharyngotonsillitis, were included in study

2. Children between ages of 5 to 15 years

3. Children with positive Rapid Antigen detection Test (RADT) for Streptococcus Pyogenes

Exclusion Criteria:

1. Immunocompromised children

2. Children with known hypersensitivity to Penicillins (esp Coamoxiclav and Benzyl penicillin)

3. Children with liver or renal failure

4. Children who were already using any oral or parenteral antibiotics