Comparison of Intravenous Ibuprofen and Paracetamol in Patients With Low Back Pain Presented to the Emergency Department

• Status: Unknown status
• Trial end date: 2017-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Currently, Paracetamol and Ibuprofen are widely used by emergency physicians in Turkey for the pain treatments.

The objective of the study was to assess whether intravenous Paracetamol has superior Low Back Pain reduction will compare with Ibuprofen in emergency department (ED) adults.

Half of the participants will receive Paracetamol and the other half will receive Ibuprofen.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Pamukkale University
• Treatments: Acetaminophen; Ibuprofen

Criteria

Inclusion Criteria:

• Patients who presented with complaints of low back pain to the emergency services ,

• Patients whose complaints have started in the last week,

• Younger than 21 years old,

• older than 80 years old,

Exclusion Criteria:

• Pretreatment linear 100-mm visual analog scale (VAS) pain score less than 40 mm,

• Patients who have drop foot, paralysis and other neurological symptoms in physical examination.

• Patients with blood pressure less than 90mmHg in the arrival of emergency services.

• Patients with malignancy, cauda equina syndrome, ankylosing spondylitis, rheumatoid arthritis or inflammatory arthritis contain any of the disease in his/her CV.

• Patients with any history of chronic pain syndrome.

• Patients who receive pain killers, antidepressants, anticonvulsants, muscle relaxants, steroids within 6 hours before the ED visit,

• Patients have a history of active peptic ulcer disease,

• Patients who have signs of peritoneal irritation,

• Patients had a fever (>37.9)

• Allergy or previous adverse reaction to the studied drugs(Ibuprofen, Paracetamol), received agents to inhibit the secretion of acid (PPIs or histamine-2 receptor antagonists), antispasmodics, or nonsteroidal anti-inflammatory drugs

• were pregnant or breast-feeding,

• inability to comprehend the VAS evaluation,

• or refused to participate in the study