Comparison of Laminaria and Misoprostol for Cervical Preparation Before Second Trimester Surgical Abortion

• Status: Completed
• Trial end date: 2010-06-01
• Target enrollment: 0
• Participant gender: Female

Summary

This study compares the effectiveness of cervical preparation before second trimester abortion using laminaria versus vaginal Misoprostol.

The investigators hypothesize that medical preparation of the cervix with vaginal Misoprostol is superior to mechanical preparation using laminaria.

The investigators believe that medical preparation makes the procedure easier to perform, equally safe, without addition of pain or discomfort.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Wolfson Medical Center
• Treatments: Misoprostol

Criteria

Inclusion Criteria:

• Pregnant patients with a viable singleton

• Pregnancy 14-20 weeks of gestation

• Admitted for termination of pregnancy

Exclusion Criteria:

• Contraindication for administration of Misoprostol

• Patients with more than one previous cesarean section scar

• Patients with impaired coagulation

• Significant pulmonary or cardiac disease

• Non viable pregnancy

• Placenta accreta or previa by ultrasound