The primary purpose of this study is to show, through a controlled masked clinical study of
subjects with ocular hypertension (OHT), that latanoprost increases the low uveoscleral
drainage of aqueous humor back to normal levels, and timolol maleate reduces the formation of
aqueous humor below normal. Both of these mechanisms will effectively reduce intraocular
pressure (IOP).
The secondary purpose is to assess the effects of both latanoprost and timolol maleate on the
fluorophotometric outflow facility, and episcleral venous pressure and on all parameters over
time.