Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support

• Status: Recruiting
• Trial end date: 2024-09-30
• Target enrollment: 0
• Participant gender: Female

Summary

To evaluate whether single euploid embryo transfer in NC without routinely administered LPS is non-inferior to NC with routinely administered LPS.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: ART Fertility Clinics LLC
• Treatments: Progesterone

Criteria

Inclusion Criteria:

• Age: 18 to 40 years

• Regular ovulatory cycles

• Availability of at least one euploid embryo after Trophectoderm biopsy for PGT-A on day 5 or day 6

• Detection of ovulation by P4 rise > 1.0 ng/ml after LH surge

• P4 value of at least 5 ng/ml on day 4 after ovulation

Exclusion Criteria:

• History of repeated pre-menstrual spotting

• Factors affecting the implantation through anatomical changes of the uterus / ovaries or the tubes (adenomyosis, Asherman syndrome, endometriosis, uterine fibroids / polyps, isthmocele with intracavitary fluid presence, hydrosalpinx….)