Comparison of Loading Strategies With Antiplatelet Drugs in Patients Undergoing Elective Coronary Intervention
Status:
Terminated
Trial end date:
2018-11-01
Target enrollment:
Participant gender:
Summary
Use of high loading doses of clopidogrel (antiplatelet drug) just before coronary
interventions is associated with improved outcomes after coronary stenting. However the onset
of platelet inhibition after clopidogrel loading takes 2 to 4 hours and its action if very
variable. A way to overcome this limitation is loading with a more potent antiplatelet drug
such as prasugrel. Therefore in the current study the investigators want to compare loading
with 60 mg prasugrel (potent antiplatelet drug) and loading with clopidogrel (standard drug)
in patients undergoing elective coronary intervention.