Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis
Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
Participant gender:
Summary
This study will be conducted to find out whether low dose or high dose cyclophosphamide
therapy is effective in the treatment of proliferative lupus nephritis.It will also compare
the side effects and risks of infection in low dose and high dose cyclophosphamide group.
Half of the participants will receive a low dose cyclophosphamide for 3 months and half will
receive high dose cyclophosphamide therapy monthly for 6 months followed by azathioprine 2
mg/kg.
Phase:
Phase 4
Details
Lead Sponsor:
Jawaharlal Institute of Postgraduate Medical Education & Research