Comparison of Meperidine and Sufentanil Added to 0.5% Hyperbaric Bupivacaine for Spinal Anesthesia in Cesarean Section

• Status: Recruiting
• Trial end date: 2021-08-01
• Target enrollment: 0
• Participant gender: Female

Summary

Subarachnoid block is a widely used anesthetic technique for cesarean section. To improve the quality of analgesia and prolong its duration, the addition of intrathecal opioids to local anesthetics has been encouraged.

In a double blind randomized controlled trial, 60 parturient women ASA 2-3 scheduled for elective cesarean delivery under spinal anesthesia will be randomly divided into 2 groups: Group 1 will receive sufentanil 5 μg and Group 2 will receive meperidine 12.5 mg. In every group, 0.5% heavy bupivacaine 10 will be added.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Makassed General Hospital
• Treatments: Bupivacaine; Meperidine; Sufentanil

Criteria

Inclusion Criteria:

• pregnant women with American Society of Anesthesiologist (ASA) 2-3

• scheduled for elective cesarean section.

Exclusion Criteria:

• refuse to participate in the study,

• requiring emergency obstetric care,

• ASA IV or V,

• having systemic diseases,

• a known fetal anomaly,

• placenta previa,

• abruption placenta

• with a history of hypersensitivity or allergy to any of the study drugs,

• operation time longer than 1.5 hour,

• blood loss more than 1500 millilitres,

• those with any contraindication to the technique proposed,