Comparison of Metformin and Pioglitazone in Regulating Menstrual Irregularities and Hyperandrogenism

• Status: Unknown status
• Trial end date: 2019-01-01
• Target enrollment: 0
• Participant gender: Female

Summary

To compare metformin with pioglitazone in improving menstrual irregularities and hyperandrogenism in women with PCOS so that an alternate and better treatment option will be available for hyperinsulinemia in pcos patients.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Dow University of Health Sciences
• Treatments: Metformin; Pioglitazone

Criteria

Inclusion Criteria:

1. women of age 18-40 with primary or secondary infertility.

2. Polycystic ovarian syndrome daignosed using rotterdam criteria.

3. Not taken any medication before for PCOS.

Exclusion Criteria:

1. Women having type 1 or type 2 diabetes mellitus.

2. Abnormal kidney or liver function.

3. Hypertension or heart disease.

4. Gonadotrophin induction or ovarian drilling before will not be included in this study.