Comparison of Montelukast and Azelastine in Treatment of Moderate to Severe Allergic Rhinitis
Status:
Recruiting
Trial end date:
2021-12-15
Target enrollment:
Participant gender:
Summary
Comparison of Montelukast and Azelastine In treatment of Allergic Rhinitis Allergic intent is
one of the most common diseases of the respiratory system that has a devastating effect on
the quality of life. The importance of studying this disease can be seen from the high
prevalence of this diseas. In addition to the high prevalence, due to the reducing effect of
this disease on the economy and academic performance of patients, a great burden is imposed
by this disease on the country's health care system.Also finding the best treatment of
allergic can help to control of Asthma if exists concurrently.
Inflammation of the nasal mucosa following the release of IgE can be shown as symptoms of
runny nose, sneezing, nasal congestion.Many studies have been done in the field of allergic
rhinitis to increase the cost-effectiveness of treatment of this complication. Among the
treatments for this disease is the use of antihistamine nasal sprays such as Azelastine.
Combination therapies such as combining Mometason furoate or fluticasone with Azelastine or
Montelukast can also be mentioned. However, there is still a long way to go to find the best
drug combination to reduce the economic and human costs to the global health system. Due to
the high prevalence of allergic diseases such as allergic rhinitis, finding the best
treatment or management of such diseases plays an important role in improving the quality of
life and reducing the economic burden on society.