Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery
Status:
Unknown status
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the postoperative systemic inflammatory response
syndrome (SIRS) rates undergoing retrograde intrarenal surgery (RIRS) after multiple-,
single-, zero-dose of ceftriaxone prophylaxis in a prospective randomized trail.
The investigators will enroll 450 patients who are candidates for RIRS in the investigators
study. By simple random sampling technique, patients will be assigned to three groups
(multiple-, single-, zero-dose of ceftriaxone prophylaxis,respectively). In addition to the
difference of usage of ciprofloxacin prophylaxis, the rest of the procedure is the same in
all three groups.The end point of the study is the comparison of outcome of procedure
including SIRS rate, stone free rate (SFR), operation time, length of stay,and hematuresis.