Comparison of Nadifloxacin Cream Alone and With Benzoyl Peroxide Solution in the Treatment of Acne

• Status: Unknown status
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether using of nadifloxacine 1% cream and benzoyl peroxide 5% solution together is more effective than using nadifloxacine alone in the treatment of mild to moderate facial acne.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Marmara University
• Treatments: Benzoyl Peroxide; Nadifloxacin; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Clinical diagnosis of mild to moderate facial acne vulgaris

• Must have at least 10 inflammatory and/or non-inflammatory and no more than 3 nodulocystic acne lesions

Exclusion Criteria:

• Nodulocystic acne lesions more than 3 and pure comedonal acne

• Additional truncal acne needs systemic therapy

• Usage of topical treatments for acne in last 2 weeks, systemic antibiotic in last 4 weeks, systemic isotretinoin in last 6 months

• Application of chemical peels and laser in last 4 weeks

• Usage of hormones in last 3 months

• Clinical signs of hyperandrogenism in females

• Pregrancy and lactation

• Hypersensitivity to interventions

• Additional facial skin diseases (eg. atopic and seborreic dermatitis)

• Photosensitive disorders and usage of drugs which can trigger Photosensitive conditions