Comparison of Nasal Saline Irrigation Bottle Contamination Between Two Solutions
Status:
Unknown status
Trial end date:
2015-06-01
Target enrollment:
Participant gender:
Summary
Rhinosinusitis is one of the most prevalent diseases within the United States and leads to
decreased quality of life for patients suffering from this condition. A foundation in
treatment for rhinosinusitis is nasal saline irrigations, which are administered through an
irrigation bottle. The irrigation bottles are prone to contamination by bacterial and fungal
species despite proper maintenance.
A new commercially available irrigation solution has been created using chitosan, a natural
polysaccharide with antibacterial and antifungal properties. This research project will
examine the ability of chitosan to decrease or prevent contamination of irrigation bottles
after 1 month use by adult patients with rhinosinusitis.
Participants in this project will use either saline or chitosan irrigation solution for 1
month and then switch to the other solution for 1 month. Following 1 month of use, the
irrigation bottles will be cultured to determine if chitosan irrigation solution decreased
the contamination of the irrigation bottles.