Comparison of Nitrofurantoin and Calcium Hydroxide as Intracanal Medicaments in Alleviating Post-operative Pain
Status:
Completed
Trial end date:
2021-05-18
Target enrollment:
Participant gender:
Summary
Intracanal medicaments have been frequently used in patients with endodontic and
periradicular infection for the elimination of microorganisms. Commonly used includes Double
Antibiotic Paste, Triple Antibiotic Paste, and Calcium Hydroxide. This study aims to compare
the efficacy in alleviating pain between intracanal medicaments Nitrofurantoin and Calcium
Hydroxide Paste. 60 patients were randomly divided into 3 groups, each group having 20
patients as following: Group 1: Nitrofurantoin, Group 2: Calcium Hydroxide and Group 3:
Control. Preoperative pain was recorded using a numerical pain scale. Pre-operative pain
score was initially recorded, followed by Post-operative pain at 12, 24, 48, and 72 hours.
Nitrofurantoin has been proven to be an effective intracanal medicament in alleviating
immediate post-operative pain in patients with symptomatic irreversible pulpitis as compared
to calcium hydroxide.