Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
Status:
Recruiting
Trial end date:
2025-11-01
Target enrollment:
Participant gender:
Summary
Chronic Exertional Compartment Syndrome (CECS) in the lower leg is a debilitating condition
in highly active individuals. Pain occurs in 1 or several leg compartments upon an exertional
activity, typically running, that quickly dissipates once the activity stopped. Surgical
fasciotomy is the standard for treating lower leg CECS, but success is variable.
Complications may occur post-surgery and there is a potential for a repeat procedure.
Recovery times post-surgery also vary greatly. Conservative treatments, such as gait
retraining and botulinum toxin injections, are emerging as non-surgical options for the
treatment of CECS with success through published case reports and case series. This study
aims to evaluate the use of these non-surgical treatment options for CECS in the anterior and
lateral leg compartments with a follow up for at least 2 years across multiple study sites.
Phase:
Phase 2
Details
Lead Sponsor:
Walter Reed National Military Medical Center
Collaborator:
Uniformed Services University of the Health Sciences