Comparison of Obturator Nerve Blockade and Neuromuscular Blockade

• Status: Completed
• Trial end date: 2019-09-19
• Target enrollment: 0
• Participant gender: All

Summary

Patients diagnosed with posterolateral bladder tumors will be invited to participate in the study. Subjects will be randomized to receive an ultrasound-guided obturator block or a neuromuscular blocking agent after the induction of general anesthesia in an attempt to block the obturator reflex during surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Florida
• Collaborators: US Department of Veterans Affairs; Veterans Health Administration
• Treatments: Anesthetics; Mepivacaine; Rocuronium

Criteria

Inclusion Criteria:

• Patients ≥ 18 years of age

• Planned TURBT for unilateral or bilateral posterolateral bladder tumors

• Ability to understand and provide informed consent

Exclusion Criteria:

• Patient refusal or inability to provide informed consent

• True allergy, not sensitivity, to local anesthetics

• True allergy, not sensitivity, Propofol

• True allergy, not sensitivity, general anesthetic agents

• Pregnancy

• Severe hepatic impairment

• Evidence of infection at or near the proposed needle insertion site

• Any sensorimotor deficit of the lower extremity, whether acute or chronic

• Inability to walk without assistance

• Lower extremity joint replacement surgery in the preceding six months