Comparison of Olopatadine 0.6% and Fluticasone Proprionate 50mcg Nasal Sprays in a Two Week Seasonal Allergic Rhinitis Trial

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Comparison of two nasal sprays for the treatment of seasonal allergic rhinitis

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Alcon Research
• Treatments: Fluticasone; Olopatadine Hydrochloride; Xhance

Criteria

Inclusion:

• A history of spring/summer seasonal allergies.

• Positive skin prick test for the currently prevalent allergen of the area.

• Confirmed absence of significant anatomic abnormalities, infection, bleeding, and mucosal ulcerations on nasal examination prior to administration of test article.

• For pre-menopausal females, a negative pregnancy test prior to entry into the study, and, if sexually active, agreement to use adequate birth control methods throughout the study.

Exclusion:

• History of chronic sinusitis.

• Asthma, with the exception of intermittent asthma.

• Smokers.

• Known non-responders to antihistamines.

• Chronic or intermittent use of inhaled, oral, intramuscular, intravenous or dermal potent or super-potent topical corticosteroids.

• Chronic use of long acting antihistamines.

• Upper or lower respiratory infection within 14 days of Visit 1. Diagnosis of acute sinusitis within 30 days of Visit 1.

• Relatives of study site staff or other individuals who had access to the clinical study protocol.

• Participation in any other investigational study within 30 days before entry into this study or concomitantly with this study.