Overview

Comparison of Outcomes of Management of Bowel Obstruction Pilot Study

Status:
ENROLLING_BY_INVITATION
Trial end date:
2026-03-01
Target enrollment:
Participant gender:
Summary
The Comparison of Outcomes of Management of Bowel Obstruction (COMBO Pilot) Pilot trial is a patient-level randomized trial of a short course of dexamethasone + supportive care vs supportive care alone for patients with adhesion-related small bowel obstruction (aSBO). The goal of the COMBO trial is to answer the question: Can Dexamethasone increases the proportion of patients with resolution of aSBO with non-operative management (without complication) based on an established minimal important clinical difference.
Phase:
PHASE4
Details
Lead Sponsor:
University of Washington
Treatments:
Dexamethasone
Palliative Care