Comparison of Phenylephrine and Ephedrine in the Treatment of Hemodynamic Disorders After Spinal Anesthesia in the Elderly

• Status: Unknown status
• Trial end date: 2020-04-01
• Target enrollment: 0
• Participant gender: All

Summary

Spinal anesthesia is often used for lower limb surgery in elderly. Hypotension is a side effect of spinal block. In this study, intravenous ephedrine and phenylephrine will be compared with each other to prevent spinal anesthesia-induced hypotension, which is defined in absolute terms as a systolic blood pressure < 100 mmHg or in relative terms as a 20% fall of systolic blood pressure from baseline.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Warsaw
• Treatments: Ephedrine; Oxymetazoline; Phenylephrine; Pseudoephedrine

Criteria

Inclusion Criteria:

• elderly (age more than 65 years)

• hip fracture scheduled for lower limb surgery under spinal anesthesia

• spinal anesthesia

Exclusion Criteria:

• contraindications to spinal anesthesia

• participant refusal

• age less than 65

• bradycardia (heart rate less than 60)

• participants unable to give consent or inability to communicate