Overview
Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD)
Status:
Completed
Completed
Trial end date:
2013-10-01
2013-10-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
The purpose of this study is to compare the effects of pitavastatin and atorvastatin on adiponectin percentage change in patients with hypercholesteremia comorbid stable CAD.Phase:
Phase 4Accepts Healthy Volunteers?
NoDetails
Lead Sponsor:
Kumamoto UniversityTreatments:
Atorvastatin
Atorvastatin Calcium
Pitavastatin
Criteria
Inclusion Criteria:- Patients with dyslipidemia as defined by any of the parameters:
- HDL-C < 50 mg/dL
- LDL-C ≥ 140 mg/dL
- LDL-C ≥ 100 mg/dL and cholesterol-lowering treatment is necessary in accordance
with the investigator's judgement
- Patients who passed three months or more after acute myocardial infarction
- Patients who passed one month or more after unstable angina
- Patients who passed one month or more after PCI
- Patients with written consent by their own volition after being provided sufficient
explanation for the participation into this clinical trial
Exclusion Criteria:
- Patients with any allergy to pitavastatin or atorvastatin
- Patients with familial hypercholesterolemia
- Patients receiving pitavastatin
- Patients with severe hypertension
- Patients with renal disorders or undergoing dialysis
- Patients with hepatobiliary disorders
- Patients with hepatobiliary disorders
- Patients with family history of hypothyroidism or muscular dystrophy
- Patients with history of drug-induced hepatic disorder
- Drug abuser or dipsomaniac
- Patients with cardiogenic shock.
- Patients who hopes for pregnancy during this study
- Contraindications, Relative Contraindications, Absolute Contraindications for
Coadministration and Relative Contraindications for Coadministration for pitavastatin
or atorvastatin
- Patients who are ineligible in the opinion of the investigator