Comparison of Postoperative Delirium in Patients Anaesthetised With Isoflurane and Desflurane During Spinal Surgery

• Status: Completed
• Trial end date: 2017-06-01
• Target enrollment: 0
• Participant gender: All

Summary

Postoperative delirium (POD) is a known complication of inhalational agents used to anaesthetise patients for surgery with potential long term implications.The incidence of postoperative delirium in spine surgery is 3.3% to 3.8%.The purpose of this study is to compare the occurrence of postoperative delirium with inhalational anaesthetics namely isoflurane and desflurane in spine surgery patients.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Postgraduate Institute of Medical Education and Research
• Treatments: Desflurane; Isoflurane

Criteria

Inclusion Criteria:

• Patients scheduled for spine surgery.

• Age between 18-65 years

• American Society of Anaesthesiologists (ASA) Grade I and II patients

• Patients with Glasgow Coma Scale (GCS) of 15

• Postoperative Aldrette score > 9

Exclusion Criteria:

• Cardiorespiratory disorders

• Associated cerebral disease

• Psychiatric illness

• Electrolyte and hormonal imbalance

• History of drug abuse

• Postoperative meningitis

• Administration of high dose steroids