Comparison of Primary and Secondary Prevention of Postpartum Hemorrhage at the Community Level in Egypt
Status:
Completed
Trial end date:
2016-01-01
Target enrollment:
Participant gender:
Summary
The objective of this study is to compare two community-level strategies: either selective,
early administration of 800 mcg sublingual misoprostol to women for secondary prevention of
postpartum hemorrhage (PPH) or universal use of 600 mcg oral misoprostol at the time of
delivery for prophylaxis of PPH. The significance of this cluster randomized non-inferiority
trial is its potential to inform service delivery programs on clinical outcomes, program
feasibility, cost, and acceptability of two different community models of PPH care using
misoprostol.1. The study hypothesizes that a service delivery model that administers
misoprostol for secondary prevention is non-inferior to a model that administers misoprostol
for universal prophylaxis.
Phase:
Phase 4
Details
Lead Sponsor:
Gynuity Health Projects
Collaborators:
El Galaa Teaching Hospital Faculty of Medicine, Alexandria University Ministry of Health and Population, Egypt University of Alexandria