Overview

Comparison of Propofol Based Versus Volatile Based Anesthesia and Postoperative Sedation

Status:
Completed
Trial end date:
2013-07-01
Target enrollment:
Participant gender:
Summary
All patients undergoing cardiac surgery require intraoperative anesthesia and short-term postoperative sedation with anesthetic agents after the procedure when patient is in the intensive care unit (ICU). The clinical data obtained so far are concentrating on intraoperative use volatile agents (preconditioning) resulting in better postoperative cardiac function and less release of biochemical markers of myocardial damage. There are no studies investigating whether postoperative use of volatile agents (post conditioning) in cardiac surgical population is improving outcomes. The aim of the present study is to compare total intravenous anesthesia and postoperative sedation versus total volatile anesthesia and postoperative sedation in cardiac surgical population.
Phase:
N/A
Details
Lead Sponsor:
University Health Network, Toronto
Treatments:
Anesthetics
Isoflurane
Propofol
Sevoflurane