Comparison of Refined and Crude Indigo Naturalis Ointment in Treating Psoriasis

• Status: Completed
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To compare the efficacy and safety of refined indigo naturalis ointment with that of crude ointment in treating psoriasis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Yin-ku Lin

Criteria

Inclusion Criteria:

• Patients were had received a diagnosis of plaque psoriasis based on clinical assessment by two dermatologists at least a one year prior to entry into the study;

• Patients had mild to moderate plaque psoriasis with bilateral symmetric lesions; were adults aged 20 to 65 years;

• Patients were in good general health.

• Female patients of childbearing age agreed to continue using birth control measures for the duration of the study.

Exclusion Criteria:

• Patients had non-plaque (i.e., pustular, guttate, or erythrodermic) or drug-induced forms of psoriasis; total body surface involvement of more than 60%;

• Patients had a history of allergy to indigo naturalis.

• Patients were excluded if they have received systemic therapy within 4 weeks before enrollment, phototherapy within 3 weeks, or used topical psoriasis agents within 2 weeks before enrollment.

• Patients had included usage of medications that affect psoriasis during the study and unwillingness to comply with study protocol.