Comparison of Remimazolam and Dexmedetomidine for Intraoperative Sedation

• Status: Not yet recruiting
• Trial end date: 2023-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the sedation efficacy of dexmedetomidine and remimazolam for intraoperative sedation during regional block.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Seoul National University Hospital
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• Patient scheduled for lower extremity surgery under regional anesthesia, aged 19-70, of ASA class I or II.

Exclusion Criteria:

• Patient refusal

• Contraindications to regional or neuraxial anesthesia (patient refusal, increased intracranial pressure, infection at puncture site, underlying neurologic disease, severe hypovolemia, aortic or mitral stenosis, thrombocytopenia or coagulopathy)

• Contraindications to dexmedetomidine or remimazolam administration

• Allergy to dexmedetomidine or remimazolam

• Baseline MOAA/S score of 4 or less

• Pregnancy

• Other conditions considered unsuitable by the investigators