Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess the comparative efficacy of retinol 1.0% and tretinoin 0.02% in minimizing wrinkles, discoloration, roughness, and other signs of moderate to severe photodamage. Our hypothesis is that both products will be of comparable benefit.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Johns Hopkins University
• Treatments: Retinol palmitate; Tretinoin; Vitamin A

Criteria

Inclusion Criteria:

• Age 35 or over

• Moderate to severe photodamage

Exclusion Criteria:

• History of facial cosmetic surgery, facial resurfacing procedures, deep peels, or facial fillers

• History of keloids or hypertrophic scars

• Use of oral steroids or oral retinoids (such as Accutane) in past 6 months