Comparison of Seasonal Allergic Rhinitis Treatment With 2 Antihistamines Used in Combination With Intranasal Corticosteroid

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the efficacy of Olopatadine Nasal Spray with Azelastine Nasal Spray when treatments are utilized in conjunction with Fluticasone Nasal Spray for the treatment of seasonal allergic rhinitis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Alcon Research
• Treatments: Azelastine; Fluticasone; Histamine Antagonists; Histamine H1 Antagonists; Olopatadine Hydrochloride

Criteria

Inclusion Criteria:

• Able to provide consent/assent

• History of spring/summer allergic rhinitis

• Positive skin prick and/or intradermal test

• Absence of significant anatomic abnormalities, infection, bleeding, and mucosal ulcerations

• Non-pregnant (where applicable)

• Able to complete daily diary

Exclusion Criteria:

• Smoker

• Concurrent disease such as rhinitis medicamentosa or large obstructive nasal polyps

• History of current chronic sinusitis

• Asthma

• Use of anti-allergy immunotherapy, corticosteroids, chronic use of long acting antihistamines

• History of severe, unstable, or uncontrolled cardiovascular, hepatic, renal and/or other diseases/illnesses

• History or evidence of nasolacrimal drainage system malfunction