Comparison of Short Duration Levetiracetam to Extended Course for Seizure Prophylaxis After Subarachnoid Hemorrhage (SAH)

• Status: Unknown status
• Trial end date: 0000-00-00
• Target enrollment: 460
• Participant gender: Both

Summary

Our primary objective is to compare two treatment options for prevention of seizures following a subarachnoid hemorrhage and determine if a short-course regimen of levetiracetam is as efficacious in the prevention of in-hospital seizures when compared to an extended course.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Washington University School of Medicine
• Treatments: Etiracetam; Piracetam
• Last Updated: 2012-03-21

Criteria

Inclusion Criteria:

1. Age >18 years of age

2. Diagnosis of spontaneous SAH

Exclusion Criteria:

1. SAH secondary to trauma or arteriovenous malformation

2. Early death (defined as death within 3 days of presentation)

3. Known allergy to levetiracetam

4. Know seizure history on chronic AEDs

5. Pregnancy

6. Current incarceration