Overview

Comparison of Single and Combination Diuretics in Low-Renin Hypertension

Status:
Unknown status
Trial end date:
2015-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether the routine combination of optimal thiazide and K+-sparing diuretic will both increase efficacy of BP reduction and reduce risk of glucose intolerance; and whether K+-sparing diuretics alone may have a neutral or even beneficial effect upon glucose tolerance.
Phase:
Phase 4
Details
Lead Sponsor:
University of Cambridge
Collaborators:
Barts & The London NHS Trust
Imperial College London
King's College London
University of Birmingham
University of Dundee
University of Edinburgh
University of Glasgow
University of Leicester
Treatments:
Amiloride
Diuretics
Hydrochlorothiazide