Overview

Comparison of Skin Sympathetic Nerve Activity According to Different Anesthetics

Status:
Unknown status

Trial end date:
2020-12-01

Target enrollment:
0

Participant gender:
All

Summary

Skin sympathetic nerve activity (SKNA) has recently been discovered from the electrocardiogram obtained from healthy volunteers. The raw physiologic electric signal from electrodes placed on the skin was reprocessed through filtering and integration using software to produce the SKNA signal. However, no study has yet provided knowledge on the effect of anesthetics on SKNA during general anesthesia.

Phase:

N/A

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Seoul National University Hospital

Treatments:

Anesthetics
Desflurane
Fentanyl
Isoflurane
Pharmaceutical Solutions
Propofol
Remifentanil
Sevoflurane

Criteria

Inclusion Criteria:

- Scheduled to undergo elective transurethral procedures under general anesthesia

Exclusion Criteria:

- Diagnosed with autonomic dysfunction

- Current use of beta blockers

- Cardiac arrhythmia

- Absolute indication for either TIVA or inhalants, absolute contraindication for either
TIVA or inhalants (adverse effects on either propofol or remifentanil, risk of
malignant hyperthermia)