Comparison of Subconjunctival 5-Fluorouracil (FU) Injection and Mitomycin C for Treatment of Early Bleb Failure
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
purpose : to evaluate and compare the effectiveness and complication of 5-FU injections and
MMC drop in management of early bleb failure .
Design:Randomized clinical trial Methods:Patients with low injected bleb in first month after
filtering or combined surgery with MMC which don't respond to high frequent topical steroids
and removal of releasable sutures will be randomize to either 5-FU injection or Mitomycin
drop 0.02%.For each patient slit photograph in first day of recruiting,first two weeks and
first and third month will be obtained.Patients will follow for at least 3 months and IOP
,bleb configuration will check as primary outcome measures.Preoperative and postoperative
data,complications,and the need for further surgical procedures will be evaluated.