Comparison of Tacrolimus 0.1% and Clobetasol 0.05% in the Management of Symptomatic Oral Lichen Planus

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This clinical study is carried out to assess the efficacy of Tacrolimus and Clobetasol in symptomatic Oral Lichen Planus.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Peradeniya
• Treatments: Clobetasol; Tacrolimus

Criteria

Inclusion Criteria:

• Clinically and Histologically proven Oral Lichen Planus

• Symptomatic

Exclusion Criteria:

• topical/ systemic medication for OLP in the previous three months

• contraindication for medications use such as a history of allergy to either corticosteroids/ tacrolimus

• immunosuppression, or pregnant / lactating females

• lichenoid reactions either drug induced or due to dental amalgam

• diabetes mellitus and on oral hypoglycemic drugs

• systemic involvement such as concurrent skin/genital lesions