Comparison of Three Different Prophylactic Treatments of Postoperative Nausea and Vomiting (PONV) in Children
Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
Participant gender:
Summary
Incidence of postoperative nausea and vomiting (PONV) in children after tonsillectomy with or
without adenoidectomy may be as high as 75%.
Several medications may prevent and treat PONV, such as steroids, antidopaminergic drugs and
serotonin (5-HT3) antagonists. The objective of this study is to compare three prophylactic
antiemetic treatments:
- dexamethasone alone (250 mcg/kg)
- dexamethasone (250 mcg/kg) + droperidol (10 mcg/kg)
- dexamethasone (250 mcg/kg) + ondansetron (150 mcg/kg).