Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Propofol is a popular intravenous drug to induce anesthesia but it causes local pain with an incidence between 40 and 90%. Three different strategies to prevent propofol induced pain will be studied compared with placebo. Pain will be scored with a four-point scale.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hospices Civils de Lyon
• Treatments: Ephedrine; Ketamine; Lidocaine; Propofol

Criteria

Inclusion Criteria:

Healthy adults (ASA 1-2) for scheduled surgery under general anesthesia with propofol

Exclusion Criteria:

• pregnant

• sedative or analgesic drug 24h before surgery

• allergy with drug used in the study

• difficulty of communication

• absence of informed written consent