Comparison of Topical 0.15% Gancyclovir Gel Versus 0.3% Hypromellose Gel for the Treatment of Herpes Zoster Keratitis

• Status: Terminated
• Trial end date: 2020-05-11
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to evaluate the efficiency of topical gancyclovir 0.15% in the treatment of herpes zoster keratitis. Half the patients will receive the study drug while the other half of the patients will receive the placebo

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Northwestern University
• Collaborator: Bausch & Lomb Incorporated
• Treatments: Ganciclovir; Ganciclovir triphosphate

Criteria

Inclusion Criteria:

• age 18 and above

• have not been on gancyclovir gel or any other form of topical antiviral therapy for the past month

• able and willing to attend subsequent follow-up visits

Exclusion Criteria:

• Associated retinitis

• patients who are allergic to gancyclovir

• patients who will require systemic or intra-vitreal gancyclovir therapy

• patients who are pregnant or breastfeeding