Comparison of Triamcinolone Acetonide Mucoadhesive Film and Licorice Mucoadhesive Film Effect on Lichen Planus
Status:
Completed
Trial end date:
2015-04-01
Target enrollment:
Participant gender:
Summary
Introduction :Oral lichen planus (OLP) is one of the most common disorders of the oral cavity
which is basically a chronic and inflammated mucocutaneous .There is no cure for OLP
currently. The main focus of treatment is to reduce the duration and severity of the
symptoms. This study was designed to determine and compare the parameters of improvement in
patient symptoms and lesions caused by oral lichen planus by using triamcinolone acetonide
mucoadhesive film and licorice mucoadhesive film.
Methods and materials :The study was randomized by double-blind clinical trial . Patients
with symptomatic OLP who referred to the Oral Medicine School of Dentistryin Medical Sciences
in Isfahan University participated voluntarily. The patients were divided into two groups
that were including 30 samples in each group. The first group was treated with triamcinolone
mucoadhesive film and the second group were treated with licorice mucoadhesive film. Data
were analyzed by using the Mann-Whitney test and t-test in SPSS software.