Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant

• Status: Recruiting
• Trial end date: 2020-08-04
• Target enrollment: 0
• Participant gender: All

Summary

Investigators observed the clinical and radiographic healing of periapical lesion using Chitosan mixed with calcium hydroxide and compared it with triple antibiotic paste when used as intracanal medicament in 3months, 6 months and 12 months.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Dr. D. Y. Patil Dental College & Hospital
• Treatments: Anti-Bacterial Agents; Antibiotics, Antitubercular; Calcium; Calcium, Dietary; Chitosan; Disinfectants

Criteria

Inclusion Criteria:

• Patients aged between 18 and 40 years Periapical lesion (not more than 5mm) radiographically.on single rooted teeth

• Roots with closed apex.

• Systemically healthy patients.

Exclusion Criteria:All patients who respond positive to allergic patch test [triple antibiotic paste] and drugs.

• Teeth with previous endodontic therapy performed.

• Patients with a history of any systemic diseases.

• Pregnant and lactating women.

• Tooth associated with vertical root fracture and coronal perforation.

• Tooth affected with calcific degeneration.

• Presence of external or internal root resorption.

• Blunderbuss apex.