Comparison of Two Application Techniques for LET Gel

• Status: Completed
• Trial end date: 2019-11-12
• Target enrollment: 0
• Participant gender: All

Summary

Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs. once for 30 minutes prior to suturing simple lacerations in children aged 7-17 years.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
• Collaborators: Children's Hospital of Orange County; Children’s Hospital of Orange County
• Treatments: Epinephrine; Epinephryl borate; Lidocaine; Racepinephrine; Tetracaine

Criteria

Inclusion Criteria:

• Simple <= 3cm lacerations requiring suturing (as decided by clinician care providers)

• Plan to suture with simple interrupted sutures

Exclusion Criteria:

• Lacerations involving the hands, feet, genitals, tongue, mucus membranes, nose, ears, or occurring over joints

• Patients whose primary language was neither English nor Spanish

• Developmentally delayed or disabled patient such that they were unable to give a pain score

• Patients requiring procedural sedation or anxiolysis with oral or intranasal midazolam