Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension

• Status: Recruiting
• Trial end date: 2022-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 8 mcg) in management of maternal hypotensive episode after spinal block during cesarean delivery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Mersin University
• Treatments: Bupivacaine; Norepinephrine

Criteria

Inclusion Criteria:

• Woman,

• ASA I-II,

• 18-49 age range,

• Actual body weight >50 kg,<90 kg

• Actual height >150cm, <180cm

• Patients undergoing surgery under elective conditions and emergency cases for non-bleeding reasons

• Fasting period is appropriate,

• Term pregnancy (38-42 weeks),

• Patients without cardiovascular disease

• Spinal block that does not reach the high level (- Patients without diagnosis of stage 2 or higher hypertension hypertension (Stage 2 hypertension is defined as a systolic blood pressure of more than 160 mmHg and a diastolic blood pressure of more than 90 mmHg.),

• Patients without vasoactive drug use,

• Preop Systolic Blood Pressure >90 mmHg,

• Bleeding less than 750 ml,

• Patients who signed the informed consent form to be included in the study

Exclusion Criteria:

• ASA III-IV,

• Pregnant women outside the age range of 18-49,

• Actual body weight >90kg, <50kg

• Actual height >180cm, <150cm

• Patients with inappropriate fasting time

• Preterm pregnancy (<38 weeks) or postterm pregnancy (>42 weeks)

• Bleeding amount more than 750 ml

• Emergency surgery with bleeding (previa, placental abruption, etc.)- Pregnant with cardiovascular system disease,

• High block level (>T4)

• Having a diagnosis of stage 2 or higher hypertension hypertension (Stage 2 hypertension is defined as a systolic blood pressure of more than 160 mmHg and a diastolic blood pressure of more than 90 mmHg.),

• Use of vasoactive drugs,

• Preop Systolic Blood Pressure <90 mmHg

• Patients who did not sign the informed consent form to be included in the study