Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section

• Status: Completed
• Trial end date: 2012-07-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Laval University
• Treatments: Carbetocin; Oxytocin

Criteria

Inclusion Criteria:

• ≥ 18 years old

• ≥ 37-week pregnancy

• singleton pregnancy

• elective cesarean section with a low transverse incision

• ASA I or II

Exclusion Criteria:

• Personal history of uterine atony or postpartum hemorrhage

• Abnormal placental implantation (known or suspected)

• > 3 cesarean sections in the past

• Personal history of a classic uterine incision

• Estimated fetal weight > 4500g

• Hemoglobin < 100 g/L

• Regular use of tocolytic drugs

• Cesarean section under general anesthesia

• Known allergy to carbetocin

• Refusal

• Inability to obtain informed consent