Comparison of Two Doses of Intranasal Dexmedetomidine as Premedication in Children
Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
Intranasal dexmedetomidine has shown to be an effective sedative when used prior to
anaesthetic induction as premedication. 1mcg/kg intranasal dexmedetomidine was used in
previous study and it produced satisfactory sedation in more than 50% of the children at the
time of anaesthetic induction with no adverse effect. In this study we aim to compare 1mcg/kg
with 2mcg/kg intranasal dexmedetomidine in children. We expect more children would attain
satisfactory sedation prior to anaesthetic induction when higher dose is used.