Comparison of Two Kinds of Postoperative Analgesia After Amputation

• Status: Unknown status
• Trial end date: 2016-08-01
• Target enrollment: 0
• Participant gender: All

Summary

Pain after amputation is a significant problem among amputees. Phantom limb pain may appear in up to 85% of patients and is usually resistant to a wide variety of treatments.It is believed that regional anesthesia, by preventing the establishment of central sensitization, may play a role in reducing the incidence of acute and chronic pain. Therefore the investigators will compare two methods of postoperative analgesic after after amputation by their efficiency and complication.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Guangzhou General Hospital of Guangzhou Military Command
• Treatments: Analgesics; Dezocine; Flurbiprofen; Flurbiprofen axetil; Palonosetron; Pentazocine; Ropivacaine

Criteria

Inclusion Criteria:

1. Patients of American Association of anesthetists（ASA）Grade 1 or 2

2. Aged between 18 and 65 years

3. Undergoing elective total knee replacement

Exclusion Criteria:

1. Mental illness can not match

2. Nerve block, epidural anesthesia contraindicated

3. People who have Slow-type arrhythmias

4. History of chronic headaches and long-term use of analgesic drugs

5. People who were postoperative consciousness, language or hearing impaired