Comparison of Two Rhythm of Administration of Prostaglandin Gel for Induction of Labor

• Status: Recruiting
• Trial end date: 2021-12-16
• Target enrollment: 0
• Participant gender: Female

Summary

The study compares two rhythms of administration of prostaglandin vaginal gels for cervical priming before induction of labor in term patients. In our institution, prostaglandin gels are given for a maximum of three times, with induction by oxytocin and amniotomy the day after the last gel whatever Bishop score has been obtained. This management results in some patient spending four days in hospital before delivery. The aim of the study is to compare our classical management scheme with a reduced interval between to gels, of 12h instead of 24 h. The primary outcome will be the time elapsed between the first prostaglandin gel and delivery. Tolerance of both management patterns will also be evaluated through a satisfaction survey.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Center of Martinique
• Treatments: Dinoprostone

Criteria

Inclusion Criteria:

• Patients above 18 years

• Gestational age ≥ 37 weeks

• With indicated induction of labor and initial Bishop score under 6

• Without any contraindication to vaginal delivery

• Who consent to participate to the clinical research

• With French Medical Public Insurance

Exclusion Criteria:

• Multiple pregnancy

• Previous uterine scar (for myomas or cesarean section)

• Fetus not in cephalic presentation

• Allergy to prostaglandins

• Who not consent to participate to the study