Overview

Comparison of Two Treatment Regimens to Reduce PA Infection in Children With Cystic Fibrosis

Status:
Completed
Trial end date:
2009-08-01
Target enrollment:
Participant gender:
Summary
Cystic fibrosis (CF) is a chronic disease that significantly affects an individual's lung function. Antibiotic medications have been proven effective at reducing Pseudomonas aeruginosa (PA) infection, which is one of the main causes of death in individuals with CF. The purpose of this study is to compare the effectiveness of treatment based on quarterly culture results versus consistent quarterly antibiotic treatment at reducing PA infection in children with CF.
Phase:
Phase 2
Details
Lead Sponsor:
Seattle Children's Hospital
Collaborators:
CF Therapeutics Development Network Coordinating Center
Cystic Fibrosis Foundation
Cystic Fibrosis Foundation Therapeutics
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Ciprofloxacin
Pharmaceutical Solutions
Tobramycin