Comparison of Two Types of Artificial Tears

• Status: Recruiting
• Trial end date: 2023-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Hyaluronic acid (HA), a natural component of the tear film, is a well-established active ingredient in artificial tears and has been reported to improve corneal and conjunctival staining in patients with DED. Thealoz Duo (Laboratoires Thea, Clermont Ferrand, France) is a novel artificial tear preparation containing two active ingredients: trehalose, a naturally occurring disaccharide with anhydrobiotic functions in many organisms, and hyaluronate, a widely distributed anionic glycosaminoglycan polysaccharide with lubricative and water-retaining properties in biological systems. The purpose of the current study is to investigate the effect of the Hyabak and Thealoz Duo in treatment of DED.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Norwegian Dry Eye Clinic
• Collaborator: Laboratoires Thea
• Treatments: Hyaluronic Acid; Ophthalmic Solutions

Criteria

Inclusion Criteria:

• Dry Eye Severity Level (DESL) 1-3

• Equivalent between-eye DESL

Exclusion Criteria:

• Ocular infection and/or non-linked inflammation

• Corneal pathology (except KSP)

• Corneal refractive surgery or cataract surgery within 6 months prior to the study